Appearance of Disease:

This lung shows emphysema (dilated air spaces) throughout the whole lung, being gross in a zone about 4 cm wide along the lateral margin, and approximately 2 cm wide along the lower margin. The inner aspect of the lower lobe exhibits considerable destruction of the pulmonary tissue, being replaced by a large cystic cavity (bulla). There is a large amount of black pigment deposited in the lung. This is carbon, derived from tar in cigarette smoke.