Epigastric pain with radiation to the back

The aim of this topic is to consider the causes and consequences of gallstone formation, and of inflammation of the pancreas.

Learning objectives

At the completion of this topic you should be able to:

  1. Describe the anatomy of the biliary tree, the composition of bile and the factors that maintain cholesterol in solution.
  2. Discuss factors predisposing to the formation of cholesterol and bile pigment stones.
  3. Outline the pathogenesis, clinical features and complications of disease caused by gallstones within the gall bladder and cystic duct, specifically biliary colic, acute cholecystitis and chronic cholecystitis.
  4. Describe the clinical consequences of gallstones within the extrahepatic bile ducts.
  5. List other conditions causing bile duct obstruction.
  6. Describe the normal exocrine function of the pancreas and its hormonal regulation.
  7. Describe the factors predisposing to acute pancreatitis.
  8. Outline the clinical features and complications of acute pancreatitis, and the biochemical parameters that indicate a poor prognosis.
  9. Describe the pathogenesis, clinical presentation and metabolic consequences of chronic pancreatitis.
  10. Discuss the clinical features and complications of pancreatic neoplasms.
  11. Discuss the role of imaging techniques in the management of biliary and pancreatic disease.

Trial exam questions:

  1. Outline the acute and chronic complications of cholelithiasis.
  2. Discuss the causes and complications of acute pancreatitis.

Case protocol associated with this topic - 15

Other relevant protocol - 50


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