JPCalc  (Barry, 1994; J. Neurosci. Method., 51: 107-116) is a research/teaching program designed (1) to show graphically how junction potentials arise in a variety of different patch-clamp configurations and other electrophysiological situations; (2) to then enable the ready calculation of junction potential corrections, given the solution data, and (3) to show clearly how those junction potential corrections need to be applied to the appropriate physiological measurements [see review on junction potentials, J. Membrane Biol., 121, 101-117 (1991)].

The original JPCalc program has since been reprogrammed as a full Windows program  JPCalc for Windows, or JPCalcW, by Axon Instruments, Inc.  It is either available with their pClamp package, or as a stand-alone program from Professor Peter H Barry.  The cost of the JPCalcW software package, User's Manual and a laboratory license for multiple computers is US$175. So far JPCalc or JPCalcW has been purchased by more than 95 laboratories in at least 17 different countries.   This program should also run with Apple Macintosh computers provided they have a fully compatible Windows/DOS emulation package.   Further details can be obtained by e-mailing p.barry@unsw.edu.au.

To download a demonstration copy of the DOS version of JPCalc please click on JPCalc Demo Download.  Although this DOS demo version will run under Windows, it has significant limitations, which will restrict it from being used with most real experimental solutions.  For a view of the typical screen of the full Windows version of the program, JPCalcW, refer back to illustration on the home page.

To return to Liquid Junction Potential Calculator and LJP Calculations, or for other information about such calculations and mobility values, click here. 

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Peter H. Barry, Apr 27, 2004